In 2015, a symposium was organized to bring together experts to discuss the issues at hand. In 2016, with growing support and an increasingly louder voice, Food Allergy Science Initiative (FASI) was launched with the Broad Institute of MIT and Harvard. In just a short time, FASI has made tremendous progress pioneering important new discoveries – attracting talented researchers, facilitating scientific and public outreach and nurturing the food allergy community. FASI is now a multifaceted initiative that spans world-class labs across the United States. In 2021, FASI launched as an independent 501(c)(3) organization. We are now entering a new era of rationally designed approaches to allergies. Someday soon food challenges, allergen avoidance and EpiPens will be relics of the past. And this club we belong to will no longer be accepting any new members.